I haven't read that but I am guessing he's talking about a regular live mid stakes game where players play tagg poker?

He cant be talking about 2nl/5nl micro poker. Lets face it, you dont need to mix up your play even 10% of the time pf.

I think the standard 4x + 1bb is good in micro b/c we are playing a relatively tight range compared to our opponents. They're stats usually are usually 40+/8- or on the other end at 5-/2/.
We charge the 40/8 players 4xbb because we know they call with worse and we make $$ when they do that.

Sklanskys commentary is most likely related to a game that the micro's never come close to approaching.