well if he only continues with top pair only, our cbet probably takes it down 70% of the time and we should cbet for protection
when we shouldn't cbet is if our opponent floats us to take it away later or raises a lot as a bluff

against the people who only continue with top pair, of course we shouldn't barrel them because they're already calling with hands that can stand a second barrel
against people who float lots you should definitely barrel A75ss on a blank because it just looks like we have a good ace and we're up against a higher PP sometimes or a hand with 5 outs
on K52r we don't necessarily need to barrel if it's a blank because we're up against lots of smaller pps and very few second pair type hands (this is opponent dependent obv) and we should just check it down
on Qh6h5h it's just a shitty spot when we get called and I think he either has a heart+overcards or a queen+ and neither of those hands is really planning on folding so we should c/f

but then it's like we're going into situations that are opponent-dependent
so a fish that calls every cbet should be barreled off a small heart on Qh5h6hx but not someone whose range is strong on that board
or a super bad fish that has all these 5x or 33 type hands on a K52 board that will call all three streets with any pair
or someone who continues with only an ace on ace high boards (raises flush draws) should not be barreled

so you have all of these exceptions as well