its hard to say without seeing you play. obviously, most people who play badly think they play great when they obviously don't, is this you, i don't know.
I'm by no means great, I'm asking advice aren't I ?

I understand the basic maths behind play, I get relatively good reads on my regular opponents, and I try and follow the basic advice that FTR has on their site; I understand the concept of pot odds and implied odds, and can quickly work them out on the fly, but its a little hard when I should be hitting a flush/straight draw 1 out of 3, and I'm struggling to hit it 1 out of 6 (even when i fold to a good raise postflop on a draw, I'll look at the deck to see what the turn/river would have been (i know I shouldn't do it ) and I still wouldn't have hit it) and then I get beat short stacked with AA/KK to a 10 8 o/s. It makes me a little paranoid to be honest, makes me tighten up and play more passively and not chase the out alot of the time, and I'm in the habit of thinking that the odds aren't going to pay off long term (I am a scientist with a good grasp of probability theory, and I know that it should work out long term, but it hasn't for a good many months) Would the right way to get over this just be to play aggressively and take the early bust until it starts to pay off?? Or do I alter my implied odds according to what my personal probability of hitting the draws etc are ??

When you get a monster, play it like one! Raise preflop (and this is ALWAYS 3x the big blind or more! None of this pansy minimum-raise garbage). Bet the flop hard. Harder if there's a bet in front of you and a draw out there. Don't worry if they fold preflop, because you're going to be playing more hands like this with less later.
Probably linked to my playing style, but if i have a monster and get anywhere near a 3x raise preflop, everyone will fold, unless the leader is in late and decides to call (I guess I should start loosening up and playing a few more hands, yes ??). I usually bet the flop nicely to encourage some action otherwise its folds all round, and hard when I'm short stacked but my monsters don't pay off as much as I'd like them to (like the last 3 weeks being busted with KK by the leader with 8 10 o/s). I don't usually get dealt a monster until later in the game anyhow. Is this likely to change if I loosen up more (not getting dealt a monster, the action on the table )?

That sounds like a rather odd blind structure, but that's beside the point.
We try and structure the blinds so everyone has 100BB to start off with (400 chips), and the blind raises often enough to keep things moving but slow enough so everyone gets to play at least a few hands (It's still a relatively social occasion). Do you have any suggestions for a different blind structure that may work a little better ?? BTW thanks for the advice, I'll try and bluff from position a little more and a little earlier in the game and work on stealing more blinds