Same thing happened to me. I'm in the midst of a terrible run, still waiting to come out of it. My roll reached its high of $600 two days ago. Now I'm at $440. I honestly didn't imagine that I would sink like I did (especially in only 2 days) but it has been dismal.

My goals:
1. Get more sleep.
2. Tighten up. Fewer c-bets and blocking bets for a while and just play ABC. (I've already dropped from $25 NL to 10.)
3. Stop the bleeding. If the bad runs come, stop for the day instead of chasing.

Any other ideas you can think of or comments on the above?