good point miffed.

my thoughts:

at lower limit NL ring (<=50NL) (especially 6-max), you 22-99 should be good winners.

early position: limp, call pre-flop raise. then 3-bet flopped set. Play for stacks. ie. get onto it like a hooker on a hard ón

late position: raise limpers, then C-Bet underpairs on rag flop. if their is a hint (even slightly) that someone else in pot may have hit it starts to become dodgy to put any more in the middle. --- This may be where u are losing on these hands.

Use your position and knowledge of the player to assess if they have hit, and either C-bet or fold like a cheap suit.

instead of getting side tracked by the statistics with set over set etc, the follow practical example should illustrate the only situation it would come up, and may change your play.

your dealt 33 in EP (DEEP STACKS), u limp and get 4 callers.

flop J53.

now JJJ is unlikely, but 555 may be a problem, and you may sniff it depending on the player but it would be hard.

lets change you pockets to 55. now if someone has JJJ there is now what u could get away from it.