vs. sets you are 50/50 (50% he has 22, 50% he has 77) so its balanced. If you 3bet will he flat with overpairs? Or will he auto-fold like 88-JJ but continue with QQ+? If he continues with most overpairs i say 3bet. And whos to say hes not raising a draw? like 89 or 45? Both of these could easily be in his range considering hes IP.

Anyways, I think flatting might be bad if he's raising something like 88-JJ because a Q, K, or A will spook him. I think a 3bet to $10-12 is in order.